{"id":267,"date":"2019-05-25T09:00:00","date_gmt":"2019-05-25T09:00:00","guid":{"rendered":"https:\/\/shineltd.org\/publication\/prevalence-of-group-b-streptococcus-anogenital-colonization-and-feasibility-of\/"},"modified":"2019-05-25T09:00:00","modified_gmt":"2019-05-25T09:00:00","slug":"prevalence-of-group-b-streptococcus-anogenital-colonization-and-feasibility-of","status":"publish","type":"publication","link":"https:\/\/shineltd.org\/fr\/publication\/prevalence-of-group-b-streptococcus-anogenital-colonization-and-feasibility-of\/","title":{"rendered":"Prevalence of group B streptococcus anogenital colonization and feasibility of an intrapartum screening and antibiotic prophylaxis protocol in Cameroon, Africa"},"content":{"rendered":"<h2>Objective<\/h2>\n<p>To evaluate group B streptococcus (GBS) colonization prevalence and feasibility of intrapartum GBS screening\/antibiotic prophylaxis (IAP) in Cameroon, Africa.<\/p>\n<h2>Methods<\/h2>\n<p>Prospective cohort in the Cameroon Baptist Convention Health Services network. Maternity providers collected anogenital swabs from consenting term women in labor for testing by a rapid GBS-polymerase chain reaction (PCR) system. Positive tests (GBS+) resulted in initiation of intravenous ampicillin until delivery. Primary outcomes were GBS prevalence and proportion of GBS+ women receiving ampicillin before delivery and more than 4 hours before delivery.<\/p>\n<h2>Results<\/h2>\n<p>A total of 219 women were enrolled from January 10 to April 27, 2017. GBS prevalence was 12.3% (95% confidence interval [CI] 7.9-16.7) with GBS+ women more likely to reside in urban areas (19.6% vs 9.7%, P=0.004). Of 27 GBS+ women, 19 (70.4%) received ampicillin before delivery and 14 (51.9%) 4 hours or longer before delivery. A median two doses of ampicillin (interquartile range [IQR] 1-5) were given and started at a median of 105 minutes (IQR 90-155) after swab collection and 20 minutes (IQR 10-45) after GBS result. Of the 8 women who did not receive ampicillin, 7 (87.5%) delivered before test results.<\/p>\n<h2>Conclusion<\/h2>\n<p>A GBS IAP protocol is feasible in Cameroon and should be evaluated for widespread implementation in Cameroon and other low-income countries to decrease GBS-related morbidity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>International Journal of Gynecology and Obstetrics, 2019. Akila Subramaniam, Christina T. Blanchard, Ekongefeyin Sintieh Nchinda Ngek et al.<\/p>","protected":false},"featured_media":0,"template":"","topic":[],"country":[],"class_list":["post-267","publication","type-publication","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"International Journal of Gynecology and Obstetrics, 2019. Akila Subramaniam, Christina T. 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